EGFR gene copy number alteration and mutation are highly variable and scientists have been challenged to define their prognostic significance in triple-negative breast cancer.
EGFR基因拷贝数的改变和突变有很大的差异，科学家试图定义其在三阴性乳腺癌中的预后意义。
Objective: to study Somatic mutation of the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR gene) in lung adenocarcinoma patients.
目的：探讨表皮生长因子受体(EGFR)基因酪氨酸激酶域体细胞在肺腺癌患者中突变的相关因素。
In aggressive gliomas, extra copies of the EGFR gene are produced, and half of such tumors also carry an EGFR mutation, which ramps up tumor growth and portends a poor prognosis.
在侵袭性脑胶质瘤中，表皮生长因子受体基因拷贝数更高，而且一半的侵袭性脑胶质瘤伴有一个GEFR突变。这个突变增加了肿瘤的生长，伴随一个糟糕的预后效果。
应用推荐