They were then able to give the mice higher doses of radiation therapy with no ill effect by blocking a mechanism by which endothelial cells communicate with each other.

BBC: Minimising cancer care damage

But if the toxic effects were caused directly by the intended effect of the drug (blocking gamma secretase), that would raise serious questions as to whether it is safe to continue with other trials of gamma secretase drugs now ongoing at other drug companies including Bristol-Myers Squibb.

FORBES: The Man Who Predicted Eli Lilly's Alzheimer Failure

Fabrizio Sanna and colleagues at the University of Cagliari in Italy injected oxytocin into particular parts of the brains of rats and induced yawning, or blocked the effect by injecting an oxytocin-blocking chemical first.

WSJ: Matt Ridley on Why You Just Yawned | Mind & Matter