You need a substance and then that substance has to have a property that changes depending on the heat flow, i.e., depending on whether it's sensing that it's the same temperature or different temperature than something else.

你需要某种物质,它的某种性质,随着热量的流动而改变，也就是说,依赖于它是否感觉到它,与其他的物体处于相同的温度。

麻省理工公开课 - 热力学与动力学课程节选

The problem is, to avoid food poisoning, you must cook your burger or chicken to a high enough temperature to kill E. coli and other gut-wrenching bugs.

NPR: Summer Hazards: Sunburn ... and Barbecue?

Climate sensitivity is how much will the temperature change over a doubling of atmospheric CO2 (more strictly, CO2-e, taking account of methane and all the other gasses and converting them to CO2 equivalents).

FORBES: Lower Climate Sensitivity Means That Climate Change Becomes A Much Cheaper Problem To Solve