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druggability

  • 成药性

网络释义专业释义英英释义

  成药性

关键词 : 分子设计 ; 内在活性 ; 成药性 ; 先导物优化 [gap=1381]Key words: drug design; intrinsic activity; druggability; lead optimization

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  • 成药性 - 引用次数：5

    It is essential for a successful drug to possess two basic characteristics: satisfactory pharmacological action with sufficient potency and selectivity;good druggability with eligible physicochemical,pharmacokinetic and safety profiles,as well as structural novelty.

    成功的药物应具备两个要素:足够强度和选择性的药理作用,适宜的物理化学、药代、安全和结构新颖的成药性。

    参考来源 - 药物的杂泛性

·2,447,543篇论文数据，部分数据来源于NoteExpress

Druggability

  • abstract: Druggability is a term used in drug discovery to describe a biological target such as a protein that is known to or is predicted to bind with high affinity to a drug. Furthermore by definition, the binding of the drug to a druggable target must alter the function of the target with a therapeutic benefit to the patient.

以上来源于: WordNet

双语例句

  • These findings illustrate the potential druggability of transcription factors and provide a molecular basis for targeting the FOXM1 family with small molecules.

    这些发现阐明了转录因子的潜在成药性，并提供了用小分子靶向FOXM1家族的一个分子基础。

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