These regulations address track, equipment, railroad operating rules and practices, qualification and certification of locomotive engineers, control of alcohol and drug use, and other subject matters.
这些规定阐述了涉及诸多事宜,包括:轨道、设备、铁路的运营规定和操作方法、列车司机的资格鉴定和认证、酒精和药物的使用的管制等,以及其他主题。
This matters because the price of a given drug falls by more than 85% within a year of patent expiry in competitive markets like the United States.
之所以强调这一点,是因为在美国这样的竞争市场中,某一种药品的价格在专利到期的一年中下滑幅度超过了85%。
In recent years, the use of drug-carrying particles a few nanometres across has improved matters.
在最近几年,一种载体颗粒的使用使这种情况得到了改善。
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