该植入式CMOS系统晶片集合了众多无线控制/驱动电路,以及一个药物传递阵列(drug delivery array),号称是首款此类晶片。根据论文描述,SoC可释放如nonapeptide leuprolide aceta.
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By disrupting the stratum corneum structure and create pathways allowing transport of macromolecules, microneedles array can improve the transdermal drug delivery and increase the efficiency.
传统的被动式经皮给药严重受限于皮肤角质层的阻碍,利用微针阵列破坏角质层可改善皮肤对药物的渗透性,大大提高经皮给药效率。
With the development of the Micro Electro-Mechanical System(MEMS), it becomes possible for microneedles array to strengthen the transdermal drug delivery.
利用微针阵列实行局部定时地释放药物、控制药量,微针阵列的研制是微驱动器的关键。
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