One drawback is the cost. An interceptor missile costs $50,000, compared to just $500 for a Palestinian rocket.

VOA: standard.2010.07.20

That's definitely the drawback of living in a city in the Bay Area.

在城市的海湾区住就是这方面不好。

找房子不难 - SpeakingMax英语口语达人

One drawback is that most car share services have very little availability at airports.

BBC: Pay-as-you-go rental cars

If you are traveling and doing a lot of email, this is a real drawback.

FORBES: Why You Want The Microsoft Surface Pro (And Why You Don't)

Another drawback: Chicago's distance from Silicon Valley may hinder the ability to cultivate key relationships.

WSJ: A Start-Up Ecosystem Forms in Chicago