Mammalian cells make only the single-stranded variety. If a cell’s defence mechanisms detect double-stranded RNA they destroy it, to protect against infection.

哺乳动物细胞只能识别单链RNA,如果细胞的防御机制发现了双链RNA就会破坏它以保护机体不受病毒的感染。

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This aversity to double-stranded RNA means short hairpins can be used to knock out the messengers, thus nullifying the signal from the underlying gene.

哺乳动物细胞对双链RNA不识别意味着可用短发卡RNA来阻断信使RNA,从而使相应基因的信号无法传递。

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In 1998, scientists identified RNAi, a mechanism that primitive organisms use to detect and destroy virus's double-stranded RNA and any viral mRNA.

1998年，科学家发现了RNAi，这是一种原始生物用来检测和摧毁病毒的双链rna和任何携带病毒的mRNA的机制。

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Certain double stranded RNA sequences will cause in the cell a process of degradation of very specific RNA sequence.

一些双链RNA序列能够在细胞中开启,特定RNA序列的降解程序

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It turns out to activate RNA interference, you deliver double stranded RNA.

要激活RNA干扰效应的话,可以将双链RNA转进细胞

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The end result is you can design now very specific double stranded RNA sequences, that when delivered into cells again will activate this process of natural degradation of an existing messenger RNA.

最终的结果是,你现在能够设计针对性很强的,双链RNA序列,当这段序列被转入细胞后会激活,对已有信使RNA进行降解的过程

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One way in which this occurs is through "RNA interference", which involves the introduction of double-stranded RNA molecules.

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The HIV retrovirus, in particular, is a single-stranded RNA virus that duplicates itself in a host cell by converting its genetic code into double-stranded DNA that is then inserted into the host cell.

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