The risk of harm can be minimized by ensuring that prescribed medicines are of good quality, safe, effective and used by the right patient in the right dose at the right time.

通过确保具有良好质量、安全、有效的处方药品，并且在正确的时间、以正确的剂量、用在正确的病人身上，可将这种危害风险降至最低。

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Further research is needed to more accurately assess the potential beneficial and harmful effects of misoprostol and to determine the smallest dose that is effective and safe.

为更准确地评估米索前列醇可能存在的有利和有害作用和最小有效安全剂量，需要开展进一步的研究。

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Pharmacokinetic data suggest that normal doses of penicillins, cotrimoxazole and gentamicin are safe in malnourished children, while the dose or frequency of chloramphenicol requires adjustment.

药物动力学数据表明，正常剂量的青霉素、复方磺胺甲恶唑和庆大霉素对于营养不良的儿童是安全的，而氯霉素的剂量或服用频率需要调整。

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"It was a safe dose of a kids' medicine, with side effect of sleepiness, " he says.

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The National Research Council has repeatedly rejected the idea that there is a safe dose.

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Among the 102 patients in the trial, 60% of those who got the highest safe dose avoided severe disability, compared with 22% of those who got a placebo.

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