The uncertainty of estimated dose by dose-effect curve is depending on the dose rate, especially, in the low dose range the influence is remarkable.

由于剂量率的影响，利用微核剂量效应曲线估算得到的剂量值，存在较大的不确定度，尤其进行低剂量估算时更明显；

youdao

RESULTS DMOC parallelly moved the dose-effect curve of histamine or NE, but the contraction could not reach the maximum at the large amount.

结果 DMOC使NE和组胺引起动脉条收缩的量效曲线平行右移，但在高剂量时收缩不能达最大值；

youdao

CONCLUSION the Hill coefficient is considered not any physiological meanings in the mathematics model usually used in fitting pharmacodynamics s dose-effect curve.

结论常用的药效学S型剂量效应曲线拟合的数学模型中，Hill系数无生理学含义。

youdao