The main dose-limiting toxicity was marrow suppression.
主要剂量限制性毒性为骨髓抑制。
While we have not seen dose-limiting toxicity at this level with the slower infusion (without pre-medication), we have seen headache in two patients, which is a moderate adverse effect.
我们在慢速输液(没有前驱给药)的情况下还没有看到剂量限制性毒性，只看到两例患者出现头痛，是中等不良反应。
The dose limiting toxicity ssociated with this regimen was myelo suppression with grade 3~4 neutrocytopenia in 72 % of patients.
本化疗方案的剂量限制毒性为骨髓抑制，其中72 %的病人发生3～ 4度中性粒细胞下降。
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