Does it make a difference? I doubt.

我怀疑这能有什么用。

youdao

Does it make a difference to your everyday life?

它对你每天的生活有影响吗？

youdao

Information of Imminent Death or Not: Does It Make a Difference?

临近死亡的信息抑或不是：这是否存在区别？

youdao

But does it make a difference if the trainer is male or female?

VOA: special.2010.07.15

It does show that people possess these stereotypes that make a difference in their real-world behavior.

但它表明人们的这些刻板印象,会影响他们在现实生活中的行为。

耶鲁公开课 - 心理学导论课程节选

Exactly how the differences in bacteria might make vaginally born babies less prone to allergies and asthma isn't yet clear, but it does point to a difference that researchers can look at going forward.

VOA: standard.2010.06.30

Does it make a difference if you are training for a 5K or a marathon?

CNN: Information overload: Finding fitness that works for you

Does it make a difference if its customers don't like it or if they trust it at all?

CNN: How much do we really hate the TSA?

Nor does it make a difference that Komen has now reversed itself and said it plans to continue the grants to Planned Parenthood that it had early threatened to cancel.

FORBES: Will the NFL Distance Itself from the Komen Foundation?