It beats us all the time - not just with eating, but with anything we try to do and end up quitting, caving in, doing it despite our best efforts.

它在所有的事情上都打败了我们——不仅仅是关于吃东西，还有关于任何我们尝试做但最终以放弃告终的事情上，并且屈服，尽管我们做出了最大的努力还是失败了。

youdao

And yet, as human beings, we are limited. Even our best efforts do not guarantee healing.

可是作为人类，我们能力有限，有时我们尽了最大努力也未必能如愿。

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At the Office of Commercial Space Transportation, we'll certainly do our best to keep up, and to help those of you in industry to be both safe and successful in your efforts. It won't be easy.

我们商业太空运输办公室的工作人员将全力以赴，协助业内人士安全和成功地开展工作。

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The Justice Department is confident its settlement administrator "will be successful in locating the vast majority of the victims and is committed to ensuring that best efforts are made to do so, " spokeswoman Xochitl Hinojosa said.

WSJ: Victims Sought in Countrywide Case

Another doctor contacted the MPS for advice about a patient who had been diagnosed HIV positive, and who was adamant in his refusal to inform his wife, despite the doctor's best efforts to persuade him to do so.

BBC: When do you break a patient's confidence?

Unfortunately, we do not appear to be getting any closer to this envisioned world despite our best efforts and billions of dollars of investments.

FORBES: World Water Day 2013: An Inside Look at Water for People's Everyone Forever Initiative