There was a significant difference in alcoholism and the number of people who were able to get to do "the white-collar" jobs.

在酗酒和能做“白领”工作的人数上存在显著差异。

youdao

Was there a difference of opinion over what to do with the Nobel Prize money?

对于怎么使用诺贝尔奖金有不同的意见吗？

《柯林斯英汉双解大词典》

"Do you think that made much of a difference to the family?"—"I think so."

“你认为那样给全家带来了很大变化吗？”—“我觉得是。”

《柯林斯英汉双解大词典》

"I do believe that I am going to make a difference to those guys that are coming to South Africa."

VOA: standard.2010.03.26

So I keep saying I've got one thing hanging, it's the last thing I want to do, but I wanted you see how much of a difference this makes.

但是我想让大家先，明白这有多大的不同,首先让我们仔细的来看看。

麻省理工公开课 - 计算机科学及编程导论课程节选

You can do it on other instruments but on a string instrument it's the difference.

很多乐器都能奏出颤音,但弦乐器上　这种揉弦产生的颤音是不一样的

耶鲁公开课 - 聆听音乐课程节选

This is just one more piece of evidence in an interesting set of biological theorists over the past couple of decades in a variety of fields trying to demonstrate that quantum effects do make a difference in biological processes.

FORBES: When Biology and Quantum Physics Collide

These developments do not often make the headlines, but they do make a difference.

NPR: President Bush's Speech on Iraq, Sept. 13, 2007

And we do have a difference, though, when it comes to definitions of small business.

WHITEHOUSE: The White House