Scientists have known that the protein complex known as FANCI-FANCD2 responds to DNA damage and repairs cross-linking, but the details of how the complex works have been unknown.
科学家早已确信存在一种称为FANCI-FANCD2的蛋白复合物,该复合体与DNA损伤及交联修复有并,至于其作用机制尚未可知。
This is due to their ability to cope with highly dimensional complex datasets such as those developed by protein mass spectrometry and DNA microarray experiments.
这是由于它们处理高维复杂数据集的能力,例如那些由蛋白质质谱和DNA微阵列实验产生的。
This protein complex was found to bind to locations on the DNA strand that the researchers had artificially damaged, suggesting that it is directly involved in the repair process.
这种蛋白复合体被发现能够结合到研究人员在DNA链上人为损伤的部位,提示了它与修复过程有直接关系。
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