DMT1, identified as the first mammalian transmembrane iron transporter in 1997, is responsible for iron uptake from small intestine and transport from endosomes to cytoplasm.

DMT1是1997年发现的哺乳类第一个跨膜铁转运蛋白，它是近年铁代谢研究领域最重大的一项突破。

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Objective To investigate the effects of iron on the expression and regulation of divalent metal transporter 1 (DMT1) that may play an important role in the physiological brain iron metabolism.

目的探讨在脑铁代谢中发挥重要生理作用的二价金属转运蛋白1 (DMT1)的表达及其调控机制。

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