Conclusion: In treatment of severe CHF, continuous infusion of furosemide can delay diuretic resistance. Continuous infusion of furosemide is superior to bolus injection in pharmacodynamics.
结论:在CHF患者中,持续静脉滴注速尿能延缓利钠抵抗的产生,在药效学(改善心功能指标和尿量、尿电解质排泄量)方面优于间断静脉注射,且对血电解质的影响无显著差别。
参考来源 - 持续静脉滴注速尿对严重充血性心力衰竭患者心功能及利尿效果的影响·2,447,543篇论文数据,部分数据来源于NoteExpress
Diuretic resistance is a common problem in patients with chronic heart failure, which maybe related to poor compliance, impaired renal function.
充血性心力衰竭患者利尿剂抵抗问题较为常见,其原因可能与患者依从性差、肾功能损害等因素有关。
The prognosis is worse in patients with diuretic resistance. Clinician should identify diuretic resistance early, and take actions to deal with it.
利尿剂抵抗的心力衰竭预后差,临床医师应识别利尿剂抵抗,并早期采取应对措施。
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