The invention provides a methodforsynthesizing (S)-N, N-dimethyl-3-hydroxyl-3-(2-thienyl) propylamine, and relates to a key intermediate of (S)-duloxetine.
It's derived from dimethyl sulfoxide (DMSO), which was promoted as a pain reliever in the 1960s and 1970s until scientists discovered in animal tests that it caused eye damage in high doses.