Obesity drugs have proved difficult to develop, and only a few have entered the marketplace.

事实已经证明很难开发减肥药，只有少量药物进入市场。

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For developers who have Web application experience, it's not difficult to develop multimodal applications.

对于具有Web应用开发经验的开发者来说，开发多模式应用系统并不是一件困难的事情。

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Because these concerns are not easily separated, the solution can be difficult to develop and maintain.

因为这些方面不容易剥离出来，所以这种解决方案很难开发和维护。

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None of these do we have vaccines for, and it's turned out that sexually transmitted diseases for a variety of reasons, we'll come back to later, are particularly difficult to develop vaccines for.

这些病我们都没有疫苗,已经证明,对于性传播疾病,有很多原因使得,我们稍后回来再讲,针对这类疾病的疫苗特别难做出来

耶鲁公开课 - 生物医学工程探索课程节选

Supposedly this means Japanese makers find it difficult to develop saleable handsets for foreign markets.

FORBES: Unraveling the Cellphone Industry's Biggest Mystery

The PS3, by contrasy, used the infamous Cell processor and was notoriously difficult to develop games on.

FORBES: Epic Games Vice President Mark Rein Calls PS4 'A Really Perfect Gaming PC'

And because these figures are a bit iffy, it makes it more difficult to develop economic growth policies.

BBC: Stands Scotland's economy where it did?