Constitutive activation of the pathway involving these two genes appears to be a major contributor to the development of uveal melanoma. (Funded by the National Institutes of Health and others. ).
包含这两个基因的信号通路的组成性激活,可能是导致葡萄膜黑色素瘤的主要因素。
This signal pathway not only participates in regulating the development of the CNS, but also correlates with the neuron regeneration, development of glioma, and mental deficiency.
此信号通路不仅参与调节中枢神经系统的发育,而且与神经元再生、胶质瘤发生和精神发育迟缓等有关。
The development of EGFR and VEGFR pathway antagonists has been blessed by a clear appreciation of the biology targeted by these therapeutic agents.
因EGFR和VEGFR途径拮抗剂具有明确的靶向生物学特性,这些药物的开发受到一致好评。
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