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Otherwise, the medicines could lose their potency over time due to the development of resistance.

否则，随着时间推移，由于产生耐药性，这些药物可失去其效力。

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Research and development of new antibiotics isn't keeping up with development of resistance.

新抗生素的研究和开发赶不上耐药性的扩展。

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These diseases, ranging from dengue fever and malaria to West Nile virus and yellow fever, are the cause of millions of deaths worldwide, yet control methods have become a dilemma due to the development of resistance by mosquitoes and increased concern about health and environmental hazards.

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The control group showed a decrease in soleus muscle mass and strength, the development of insulin resistance, and a loss of bone mineral density and resistance to breakage.

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Dr Shulman added that the reduction could be a contributing factor to the development of insulin resistance and Type 2 diabetes because of its effect on fat burning and mitochondria production.

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