Despite these drawbacks, the first implantable pacemakers were an improvement over what had come before.

尽管有许多缺点，第一个植入式心律调整器比之过去还是一个很大的进步。

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Despite these two drawbacks, raw printing is easy to set up.

虽然有这两个缺点，原始打印很易于设置。

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Despite these drawbacks, some studies have pointed to a substantial increase in trade within the euro area arising from monetary union, for example by 20-25% in the first four years.

ECONOMIST: The supposed benefits of monetary union are cut down to size