I shall try again despite the difficulty.

虽然有困难，我会再试一次。

youdao

Despite the difficulty in deciding on the optimum city population size, such studies will go on endlessly.

尽管确定城市最优人口规模非常困难，但对其研究不会终止。

youdao

Well, what it is is easily enough explained despite the sort of difficulty and thorniness of the word.

虽然我们遇到过很多困难和挫折,但这个问题很容易解答。

耶鲁公开课 - 文学理论导论课程节选

Despite the difficulty of access, inspectors had uncovered tons of deadly chemicals, among them mustard gas.

FORBES: Eliminating This Evil

Despite the difficulty finding an O-positive donor, "we try and control the waiting time to be within two to four weeks after arrive to our center, " Lee wrote in October during e-mail exchanges with the Scott family.

FORBES: Magazine Article

Nevertheless, it is wrongheaded, and despite the sunk costs and the difficulty of reversing field in the policy world, the Clinton Administration should make a gradual but unmistakable about-face.

CENTERFORSECURITYPOLICY: Center For Security Policy