Despite his best efforts, however, he did not end up with quinine.

尽管他尽了最大的努力，他最终还是没有得到奎宁（一种治疗疟疾的药物）。

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Despite continual disinfecting efforts, he says his 169 cattle fell victim to foot-and-mouth disease last year, and like so many other farmers across the country, he had to have them killed.

尽管有持续的消毒努力，他说去年因感染口蹄病的169头牛像这个国家很多其他农场主的一样不得不被宰杀。

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He flattened his palm against the door lock, then grabbed a cookie despite his best efforts not to and stepped into the recreation room.

博兹手掌平展，抵着门锁，然后尽管他尽了最大努力来阻止自己，却还是抓起一块小甜饼，跨进了娱乐室。

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Despite his efforts, he says his site's ranking on Google has yet to improve.

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Most are fighting long, vicious, emotionally draining legal battles, and despite his efforts at handholding, "Some can't handle it, " says Mr. Lyle.

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Despite his efforts, Surrey failed to reach the Twenty20 Cup quarter-finals.

BBC: Schofield back on right track