Progress in treatment scale-up in Senegal has been achieved despite challenges posed by a centralized public health infrastructure and weak procurement and supply management systems.

尽管中央公共卫生基础结构以及薄弱的采购和供应管理系统面临着很多问题，但是塞内加尔在扩大治疗方面取得了进展。

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Despite the tremendous challenges from online retailing, traditional retailing will be here to stay for quite some time.

尽管传统零售面临着网上零售带来的巨大挑战，但它在相当长一段时间内仍将存在。

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Despite the challenges, we are likely to see more desktop applications tapping into the web.

虽然存在挑战，我们有可能看到更多的桌面应用程序向网络进军。

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Despite continuing challenges in Afghanistan, the NATO leader said the ongoing mission is indicative of NATO's continued relevance.

VOA: standard.2009.09.29

But despite the challenges, International Olympic Committee Executive Director for Olympic Games Gilbert Felli says that Vancouver organizers have done an excellent job.

VOA: standard.2010.02.21

Despite Janice Abbott's and Cherry Kingsley's efforts, the Living Library faces challenges in getting its message out.

VOA: standard.2010.02.23

Nadoll called the company's outlook promising, despite challenges like tighter competition.

FORBES: Earnings

Some conversations will not go well, but you will walk away with the feeling you did the best you could to maintain your professionalism and compassion despite challenges coming at you from multiple directions.

WSJ: Talking Cure for Health Care: Improve Doctors' People Skills

Despite challenges from his opponents, incumbent President Mahmoud Ahmadinejad was declared the overwhelming winner of the race, sparking hundreds of thousands of Iranians to take to the streets for more than two weeks to protest the election results.

CNN: Iran prisoner beaten to death, coroner says