I woke up at 8:30 knowing that the appointment was at 9:45, but despite all my plans, I still got there at 10.

我在8:30醒来，知道约定是在9:45，但不管我有什么计划，我仍然在10点到达那里。

youdao

Despite all my work, I still failed the exam.

尽管我做了种种努力，但还是没有通过考试。

youdao

Despite all my efforts to persuade him, he wouldn't agree.

尽管我尽力说服他，可他就是不同意。

youdao

"Despite the fact that the prevailing diplomatic winds these days blow in the direction of diplomacy alone, I believe with all my heart that diplomacy and sanctions are not mutually exclusive."

VOA: standard.2009.10.28

Despite all my athletic endeavors, I haven't forgotten about the most important thing, my education.

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But like everyone else, I figured that despite all of my misgivings, after decades of success with this strategy, Oracle would pull it off yet again and become a dominant player in SaaS and the Cloud.

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Personally, the price tag puts it out of my reach despite all the attractive features.

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