CONCLUSION: CsA can inhibit hypertensive cardiac hypertrophy, but large dose or longer period of application will lead to severe myocardial edema, which is dose-dependent and time-dependent.
结论：环孢霉素A可抑制高血压心肌肥大，但较大剂量或较长时间应用则会产生严重心肌水肿，并且这种作用是剂量、时间依赖性的。
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