Objective To study the developmental properties of delayed rectifier potassium currents (IK) in maturing hippocampal pyramidal neurons.
目的研究大鼠海马锥体细胞延迟整流钾电流(IK)在出生后不同发育阶段的变化。
In long-QT syndrome type 1, mutations occur in the KCNQ1 gene, which encodes the repolarizing potassium channel mediating the delayed rectifier IKs current.
在I型QT延长综合征中,KCNQ1基因发生突变,对介导延迟整流钾通道电流的复极化钾通道进行编码。
Ion channel activity had the character of voltage-dependence. Some cells, which did not exhibit sodium currents exhibited, delayed rectifier potassium currents.
并且离子通道活动具有明显的电压依赖性,在没有记录到钠电流的细胞记录到延迟整流钾电流。
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