Lifton's group found that 2 percent of the subjects carried one defective copy of one of the three genes.

Lifton小组发现2%的受试者携带三个基因中的一个缺陷基因。

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The researchers speculated that people who carry only one defective copy might be less prone to hypertension.

研究人员推测只携带一个缺陷基因的人可能更容易发生高血压。

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Surprisingly, electrophysiology studies of the family members found that people who carry only one copy of either defective gene may not develop CMT, but they are not free from nerve problems.

令人惊喜的是，针对Lupsik家族的电生理学研究表明，如果只携带有一个突变基因的话，或许可以避开CMT，然而他们也同样有神经问题。

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Some 600, 000 Americans have a less severe version caused by one defective copy. (There would be more of the double-gene victims if they didn't die young.) To get its drug approved Isis will need to study 45 patients with the severe two-gene form and a few hundred with the single-gene disease.

FORBES: Degunker

If it is safe, the medicine could also be used for patients who have a single copy of the defective gene.

FORBES

The idea of treating disease by replacing a defective gene with a working copy gained credence in 1990 with the success of the world's first gene therapy clinical tests against a rare condition called severe combined immunodeficiency (SCID).

MSN: European regulators back first gene therapy drug