NovaRx, founded three years earlier, got a big boost in late 2006 from a dream-come-true investor: billionaire David Murdock, the 85-year-old owner of Dole Food.

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Dole "starts ahead of the other candidates, " said David Keene, president of the American Conservative Union.

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Ms Scranton even hopes to attract speakers such as Bob Dole, Mr Clinton's Republican rival in 1996, David Kendall, his lawyer, and Newt Gingrich, his nemesis from the mid-1990s.

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