Combined Molecular and Clinical Prognostic Index for Relapse and Survival in Cytogenetically Normal Acute Myeloid Leukemia.
【译】结合在细胞遗传学正常的急性髓细胞性白血病的分子和复发和生存的预后指标。
Conclusions Genotypes defined by the mutational status of NPM1, FLT3, CEBPA, and MLL are associated with the outcome of treatment for patients with cytogenetically normal AML.
结论：由npm 1, FLT3, CEBPA，和MLL基因的突变状态所界定的基因型与细胞遗传学正常的急性髓细胞白血病患者的临床治疗结局之间存在相关性。
More importantly, when LSC - and HSC-related gene signatures were examined in a cohort of 160 cytogenetically normal AML patients, both signatures correlated negatively with overall survival.
更有意思的是，当对160例细胞遗传学明确的AML患者检测发现，LSC -和HSC相关基因标志与患者的总生存成负相关。
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