Those structures cover coumarins, terpenes, steroids, alkaloids and cyclopeptides, etc. , which provided a lot of basic data for drug research and development.
利用直接法和Patterson法完成了90个化合物的单晶X射线衍射结构分析和研究,其化合物涵盖了香豆素、萜类、甾体、生物碱及环肽等众多结构类型,涉及到全未知结构、疑难结构和新骨架类型的化合物,为药物研究提供了大量化合物结构的基础数据。
参考来源 - 有机分子立体结构研究与药物多晶型X射线衍射分析方法的建立·2,447,543篇论文数据,部分数据来源于NoteExpress
Studies on the Bioactive Compounds of Cyclopeptides from Microbes of East China Sea;
环肽类化合物广泛地存在于自然界中,尤其是海洋中的海绵里。
BQ-123 and 3 cyclopeptides were synthesized by solid-phase peptide synthesis (SPPS). The structures were established by MS.
应用固相多肽合成了BQ - 123和3个环肽,结构经质谱鉴定正确。
The cyclopeptides often have complex chemical structures distinct from common polypeptides (proteins) that are non-cyclic and gene-coded.
和常见的非环状基因编码的多肽或蛋白质相比,环肽结构更为复杂。
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