Cyclizing agents used are benzene chloride, oleum and so on.
所使用的缩合剂为无水醋酸钠，环化剂为氯化物。
Sulfuric acid and acetic anhydride were used as a cyclizing agent to prepare Ofloxacin intermediate. The reaction could be carried out under moderate conditions and facilitate industrial produce.
用硫酸乙酐混合物作环合剂，制备了氟嗪酸中间体．该方法具有反应条件温和、价格便宜、后处理简单的优点，适用于工业化生产。
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