Conclusion Inhibition of CRLP may reduce the DNA repair ability through blocking DNA repairing complex forming.
结论CRLP基因的表达受到抑制以后可能通过影响细胞DNA修复能力降低细胞抗紫外杀伤的能力。
Methods the plasmids which can express the truncated mutants of the TPR tandem clusters at different region of CRLP were constructed, stable transfected BEL7402 cell lines were established.
方法构建了不同TPR串联簇的截断突变体的表达质粒后，建立了稳定转染的BEL740 2细胞株。
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