He's seen many changes in the course of his long life.

他在漫长的一生中目睹了许许多多的变化。

《牛津词典》

Grandfather has seen many changes in the course of his long life.

祖父在其漫长的一生中目睹了许许多多的变化。

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Of course, she is not the only one in the family to battle with her shape - her mother has endured a life-long struggle to manage weight.

当然，她不是家族中唯一一个决心重塑身材的人-她的母亲坚持毕生的精力努力保持体形。

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But Warren Buffett remains a market cheerleader, but of course advocating his life-long beliefs in picking the right, well-researched stock-picking situations.

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"This droll-faced northern girl, who in the course of a long and happy life, took her place amongst the best we have, " said Bennett.

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You would, of course, have to wish a lot for a long life to choose to starve yourself to achieve it.

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