In THREE decades of selling cars in southern California, David Wilson has been through countless ups and downs.

戴维·威尔森在南加州做了三十年汽车销售生意，他经历过无数次市场起落。

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Since then the space program has had nearly countless ups and downs (no pun intended).

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There will be countless ups and downs, and there will be times when you will question whether starting your own business was really worth the sacrifices you are sure to make.

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The resilient and charismatic leaders of Onyx, Alkermes and Alnylam, who steered their companies through countless ups-and-downs, while creating billions of dollars of shareholder value, were also recognized.

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