...质折叠动力学(Protein Folding) 酶动力学(Enzyme Kinetice) 底物结合(Substrate Binding) 构象转变(Conformational Changes) 胞内底物运输(Substrate T)...
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Although much progress has been achieved in recent years, it is still very difficult to predict a priori the adsorption rates, orientations, or conformational changes, all of which are vital to understanding, controlling, and manipulating protein-based biological events at interface.
近几十年来,尽管人们对蛋白质吸附的研究取得了很大进展,但对蛋白质吸附的机理仍缺乏深入的了解,现在仍然不能准确预测吸附后蛋白质分子的取向以及吸附过程引起的构象变化,而这些工作对于理解、控制和利用界面上蛋白质的生物过程是非常重要的。
参考来源 - 分子动力学模拟蛋白质在固液界面的吸附·2,447,543篇论文数据,部分数据来源于NoteExpress
The conformational changes often take place upon adsorption and arose...
蛋白质分子在界面吸附后发生构象改变,引起熵增。
It indicates that protein denaturation is a sequential process for the conformational changes.
这一形式表明蛋白质变性是一个构象渐变的过程。
We use a uniformly rotating dipole, which represent the inner freedom, to describe conformational changes.
用一个匀速转动的偶极子来描述马达的构象变化,考虑了马达的内部自由度。
The other beauty about - beautiful thing about proteins is that if you make subtle conformational changes, often those changes are reversible.
蛋白质的另一个美妙之处就是,如果蛋白质发生一些小的构像改变,这些改变通常是可逆的
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