According to Ibbotson, the compound annual returns for large-cap stocks and long-term government bonds have been 9.6% and 5.7%, respectively.

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Finally, should REGN727 have safety issues which arise on long term use (CETP inhibitors come to mind), this compound will be dead.

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The long-term results are not very impressive: Over the two full market cycles Pin Oak has averaged a compound annual return of -6%, putting it 8 points behind the 500 index.

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