Objective:To explore whether detecting minimal residual disease of leukemia with hyper-methylation of the calcitonin gene as molecular genetic marker of leukemic clone to predict the prognosis.
目的：探讨以降钙素基因高度甲基化为白血病克隆的分子基因标志，检测白血病微量残留病，并预测预后的可能性。
The invention can not only make use of the nontoxic gene marker as gene probe, but also set foundations for further clone of the gene through physical mapping.
本发明不仅可利用该无毒基因的标记作探针，而且为进一步通过物理作图法克隆该无毒基因奠定了基础。
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