Objective:To explore whether detecting minimal residual disease of leukemia with hyper-methylation of the calcitonin gene as molecular genetic marker of leukemic clone to predict the prognosis.
目的：探讨以降钙素基因高度甲基化为白血病克隆的分子基因标志，检测白血病微量残留病，并预测预后的可能性。
The invention can not only make use of the nontoxic gene marker as gene probe, but also set foundations for further clone of the gene through physical mapping.
本发明不仅可利用该无毒基因的标记作探针，而且为进一步通过物理作图法克隆该无毒基因奠定了基础。
The results established the foundation of Marker Assisted Selection(MAS) of breeding , the two opposite genes Map-based clone and function study of the gene.
这些研究结果将为对生玉米的分子标记辅助选择育种、对生基因的图位克隆及对生基因的功能研究等奠定了良好的基础。
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