Accurately scaling down to mimic manufacturing processes is essential in several aspects of process validation. Chapter 4 provides further guidance and strategies for scaling down unit operations, including chromatography, chemical modification reactions, ultrafiltration, and microfiltration. In addition to general scale-down principles and parameters, the authors address specific problems and present some examples.
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Chemical modification reactions of dehalogenase YL, 109 and H-2 were carried out by various reagents.
本文用各种化学修饰剂对脱卤酶yl、109和H - 2进行化学修饰。
Chapter 4 provides further guidance and strategies for scaling down unit operations, including chromatography, chemical modification reactions, ultrafiltration, and microfiltration.
第四章对规模缩小的单元操作，包括色谱，化学改变反应，超滤和微孔过滤提供了进一步的指南和战略。
This paper describes the methods of preparation and polymerization of monomers of oxazoline. The modification of polyoxazolines by chemical reactions and their blends are introduced.
综述了唑啉单体的合成及其聚合方法，并对其聚合物的化学改性及共混物作了概述。
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