Objective:To optimize the prepartion of genistein chitosan microspheres with central composite design (CCD).

目的：采用星点设计实验，优化金雀异黄素壳聚糖微球的制备工艺，提高预测性。

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OBJECTIVE To optimize the formulation of tinidazole colon-targeted bioadhesive tablets by the central composite design-response surface methodology (RSM plus CCD).

目的通过星点设计-效应面法优化替硝唑结肠靶向生物黏附片处方。

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