The tumor suppressor p53 primarily functions as a transcriptional factor and mediates a variety of downstream functions, including cell-cycle arrest or apoptotic cell death in response to DNA damage, cell growth, differentiation, tumorigenesis and senescence.
肿瘤抑制因子p53调节了一系列重要生理过程,包括DNA损伤引起的细胞凋亡,细胞周期阻滞,细胞增殖,分化和衰老等等。
参考来源 - G蛋白偶联受体激酶5对细胞凋亡的调节及其机制研究·2,447,543篇论文数据，部分数据来源于NoteExpress
以上来源于: WordNet
N the growth cycle of eukaryotic cells. It is divided into five stages, known as G0, in which the cell is quiescent, G1 and G2, in which it increases in size, S, in which it duplicates its DNA, and M, in which it undergoes mitosis and divides 细胞周期
One of the early success stories of computational systems biology was the work done on cell-cycle regulation.
计算系统生物学的一个早期的成功故事是在细胞周期调控上所做的工作。
In normal cells, p21 ACTS like a brake to block cell cycle progression in the event of DNA damage, preventing the cells from dividing and potentially becoming cancerous.
在正常的细胞中，如果DNA受损，p 21就会像刹车一样阻断细胞周期进程以防止细胞分裂和癌变。
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