Genetics can affect the function of ion channels and reduce the seizure threshold, causing neurons.

遗传可以影响细胞膜离子通道的功能，降低惊厥阈值，引起神经元放电。

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We've found that exposure to alcohol inhibits some receptors and later activates others, causing neurons to manufacture steroids that inhibit LTP and memory formation.

我们发现酒精暴露会先抑制一些受体随后又激活其它受体，导致神经元产生抑制LTP和记忆形成的甾体物质。

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The scientists point out that alcohol isn't causing blackouts by killing neurons. Instead, the steroids interfere with synaptic plasticity to impair LTP and memory formation.

研究人员指出，酒精并不是通过杀死神经元细胞导致失忆发生的。实际上，是这些产生的甾体物质影响了突触可塑性，造成了LTP和记忆形成方面的损害。

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Dr Lloyd-Evans explains that the absence of cholesterol in the brains of SLOS sufferers means that the neurons and the central nervous system are affected, causing anything from mild personality disorders to severe malformations and multi-organ disease.

BBC: 'No-one had heard of my boys' syndrome'