BACKGROUND: Proteoglycan is the main component of cartilage endplate, which is the biochemical basis in maintaining the biomechanical behavior of cervical intervertebral disc.

背景：蛋白多糖是软骨终板的主要组成部分，是维持椎间盘力学性能的生化基础。

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Conclusion. We suggest that a genetic variation at the IGF1R gene locus is associated with spinal disc degeneration, in line with the involvement of the IGF1R gene in the cartilage metabolism.

结论：我们认为IGF1R基因位点的遗传突变，主要是与软骨代谢相关的IGF1R基因的受累，与椎间盘退行性变有关联。

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The end surfaces of the vertebral bodies are cleared of all diseased disc cartilage and readied for the metal endplates of the prosthesis.

椎体表面病变的椎间盘软骨清除干净，为金属终板假体作准备。

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