Although we get Eplerenone by another method from Δ~(9(11)) Canrenone, reacting with Acetone cyanohydrin,and then with 1NHCl,25% Sodium methoxide and H_2O_2, the yield is poor.
我们用Δ~(9(11))坎利酮先和丙酮氰醇反应，然后再与1N盐酸，25％甲醇钠以及过氧化氢反应制备得到了最终产物依普利酮，但是收率很低，有待于进一步研究。
参考来源 - 醛固酮受体拮抗剂依普利酮的合成工艺研究·2,447,543篇论文数据，部分数据来源于NoteExpress
A red compound was obtained by bio-transforming canrenone.
通过对坎利酮进行生物转化，获得一种红色的产物。
Bio-transforming the canrenone with the enzyme system of Aspergillus ochraceus SIPI-4411; By solvent extraction and silica gel column chromatography, the compound SIPI-CANR was obtained.
应用赭曲霉SIPI-4411的羟化酶系统对化合物坎利酮进行生物转化，通过溶剂萃取、硅胶柱层析，获得转化产物SIPI-CANR化合物的纯品。
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