The expression of proto-oncogene c-fos and c-myc increased with the calmodulin content,as most likely be part of the molecular mechanisms of the roles of calmodulin.
基因表达分析表明,原癌基因c-fos、c-myc随钙调素增高而表达加强,这可能是钙调素作用的分子机理之一。
参考来源 - 高表达钙调素NRK细胞模型的建立及其对细胞生长失调的影响Their interaction with calmodulin was studied by electrophoresis method, inhibited activity of Ca ̄(2+)-dependent 3', 5'-cAMP phosphodiesterase and flurescence technique.
应用电泳技术,抑制钙依赖性的磷酸二酯酶酶活方法和荧光技术研究了这些多肽与钙调蛋白的相互作用。
参考来源 - 蜂毒肽片段的合成及其与钙调蛋白的相互作用Objective To investigate the relationship between calcium leak and the expression and activity of Ca2+/calmodulin-dependent protein kinase-Ⅱ(CaMKⅡ) in myocytes of rabbits with heart failure(HF).
目的探讨家兔心衰心肌细胞钙渗漏与蛋白激酶A(PKA)和Ca2+/钙调蛋白依赖性激酶Ⅱ(CaMKⅡ)表达和活性的关系。
参考来源 - 家兔心衰心肌细胞钙渗漏与钙调蛋白依赖性激酶Ⅱ表达的关系Berbamine is a bisbenzylisoquinoline alkaloid and a natural calmodulin antagonist. Studies showed that Berbamine has anti-tumor effects and increases the leukocyte count.
小檗胺是小檗属植物中提取的双苄异喹啉类生物碱,是一种天然钙调素拮抗剂,具有抗肿瘤、促进白细胞增生等作用。
参考来源 - 钙调素拮抗剂EBB抑制人乳腺癌细胞生长的实验研究·2,447,543篇论文数据,部分数据来源于NoteExpress
N a protein found in most living cells; it regulates many enzymic processes that are dependent on calcium 钙调蛋白 [biochem]
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