You might assume that a label of Down syndrome means limitation, but when he talks, you realize how rich life can be.

你可能会认为，唐氏综合症就意味着缺陷，但患者说话时你会意识到，生活能有多么丰富。

youdao

I've found that when I talk about simplifying or minimalism in general, people are generally positive... but when you get down to specifics, they're not always so enthusiastic.

我发现，当我笼统地谈及简化或者极简主义，人们大多表现得很积极…但当我讲更细节的部分的时候，他们却总不那么充满热情了。

youdao

There is a sound scientific basis for the recommendation but, when you boil it down to a one-line exhortation, the subtleties are lost.

该提议有一个合理的科学基础，然而，当你将其概括为一句规劝，细节部分就都失去了。

youdao

You get down to brass tacks when you say, "it sounds good, but how much does it cost?"

VOA: special.2010.05.16

So now, henceforth, when you say, to declare a function, I am declaring a function here but down here am I quote unquote defining it or implementing it.

从此以后，当你说，声明一个函数，我在这里声明了一个函数,但是到这里我定义它或执行它。

哈佛公开课 - 计算机科学课程节选

I know this is a simple example, but when you mature as a programmer, one of the first things you should do when you sit down to tackle some problem is write something like this pseudo code.

我知道这是个很简单的例子，但是当你们成长为一名程序员后，当你们碰到问题后第一件事情就是,该写一些类似于,伪代码的东西。

麻省理工公开课 - 计算机科学及编程导论课程节选

But when you come right down to it, a lot of it is basic.

FORBES: Some Control Won't Convert Independent Contractors To Employees

But when you get right down to it, talk, in this context, is cheap.

ECONOMIST: Drawing no conclusions

But when you break it down, that is just five votes per precinct.

WHITEHOUSE: The White House