Mostly, he sits in a wheelchair, crippled by brittle bone disease.

由于脆骨病致残，他大多数情况下坐在轮椅上。

youdao

Bone mass decreases because of the loss of estrogen and this can lead to brittle bones.

骨量录得跌幅，因为失去雌激素，这可导致骨骼脆性。

youdao

Osteoporosis causes dramatic thinning of the bone, resulting in weak, brittle bones that can easily be broken.

骨质疏松会使你骨头戏剧性的稀释，导致虚弱，易脆的骨头。

youdao

"We think because of the long term effect of the bone, there may be stress fractures that are not repairing and I think the bone is becoming brittle, and it's not exactly as if it occurs without any warning, but it occurs suddenly with minimal trauma."

VOA: standard.2010.03.14

It can lead to serious long-term complications, such as the brittle bone disease osteoporosis, infertility and cancer of the small intestine.

BBC: Birthday link to digestive disorder

The 26 year-old was found to have abused her son, then aged two, by violently twisting him and causing him multiple fractures, but she says her family history of brittle bone disease was wrongly ruled out.

BBC: NEWS | Programmes | Real Story | My fight to be a mother

The goal: a drug against osteoporosis, the brittle-bone disease that afflicts 25 million older Americans, mostly women.

FORBES: A hail of silver bullets