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BRAF

苏氨酸蛋白激酶

特异性本试剂盒用于检测人B-Raf原癌基因丝氨酸/苏氨酸蛋白激酶(BRAF)，经检测与其它相似物质无明显交叉反应。

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黑色素瘤

...5年9月30得到美国FDA批准，用于晚期黑色素瘤(限于BRAF野生型)，之后又于2016年1月23得到美国FDA批准用于晚期黑色素瘤(不限BRAF突变状态)一线治疗[18,19]。

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靶向治疗

这些组合方法可能其重大作用，特别地在肿瘤其中PD-1/PD-L1轴是唯一对肿瘤免疫逃避的部分贡献者。Nivolumab与靶向治疗(BRAF和MEK-直接治疗)的组合也已产生显著兴趣[Hu-Lieskovan等2014]。

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短语

Anti-BRAF 黑素瘤相关蛋白抗体

Zach Braf 扎克·布拉夫

abstract: BRAF is a human gene that makes a protein called B-Raf. The gene is also referred to as proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene homolog B1, while the protein is more formally known as serine/threonine-protein kinase B-Raf.

以上来源于: WordNet

Lo said that while his team was studying resistance, they expected to find secondary mutations in BRAF.

Lo说，虽然他的团队在研究耐药性，但是他们却希望存在BRAF的二次变异。

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Mutational activation of the BRAF oncogene is the most common genetic alteration in cutaneous melanoma.

BRAF癌基因突变的激活是皮肤黑色素瘤最常见的基因改变。

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About half of all melanoma patients have a mutated BRAF gene. This mutation tells the cell to continue to grow.

将近半数的黑色素瘤患者都有BRAF基因突变，从而导致黑色素肿瘤细胞继续生长。

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更多双语例句

The drug so far has only helped patients whose tumors have the BRAF mutation.

FORBES: American Society of Clinical Oncology
Prof Richard Marais, from the Paterson Institute for Cancer Research in Manchester, was involved in the discovery of the BRAF fault.

BBC: 'Drug holidays' beat cancer drug resistance in mice
In 2002 gene researchers in the U.K. discovered that two-thirds of melanomas have a mutation in a growth-promoting gene inside skin cells called BRAF.

FORBES: Targeting Melanoma

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