CONCLUSION This preparation of BLCL is practicable and the pharmaceutical characterization showed stable.

结论脂质体制备工艺可行，药剂学性质稳定。

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OBJECTIVE to determine optimized prescription and technique for preparing brucine long-circulating liposomes (BLCL) by means of optimization screening, and to evaluate its quality.

目的通过优化手段筛选最佳处方及工艺，制备马钱子碱长循环脂质体，并评价其质量。

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Morphological characteristic of the established immortalized BLCL was observed by microscope and the expression of CD19 and CD23 on cellular surface was determined by flow cytometry.

光学显微镜下观察lcl的形态特征，利用流式细胞术分析LCL细胞膜表面分子CD 19和CD 23的表达水平。

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